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187 results

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Page 1
Did you mean nfkb a and intestine (367 results)?
m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB-mediated antiapoptotic pathway.
Zhang T, Ding C, Chen H, Zhao J, Chen Z, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M, Flavell RA, Li HB. Zhang T, et al. Sci Adv. 2022 Mar 25;8(12):eabl5723. doi: 10.1126/sciadv.abl5723. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333576 Free PMC article.
Mechanistically, we revealed that Mettl14 restricted colonic epithelial cell death by regulating the stability of Nfkbia mRNA and modulating the NF-kappaB pathway. Our results identified a previously unidentified role for m(6)A modification in colonic epithelial cells and …
Mechanistically, we revealed that Mettl14 restricted colonic epithelial cell death by regulating the stability of Nfkbia mRNA and mod …
MiR-146a protects small intestine against ischemia/reperfusion injury by down-regulating TLR4/TRAF6/NF-kappaB pathway.
He X, Zheng Y, Liu S, Shi S, Liu Y, He Y, Zhang C, Zhou X. He X, et al. J Cell Physiol. 2018 Mar;233(3):2476-2488. doi: 10.1002/jcp.26124. Epub 2017 Aug 25. J Cell Physiol. 2018. PMID: 28771774
Previous studies reported that miR-146a was involved in small intestine ischemia-reperfusion (I/R) injury, but the mechanism is largely vague. ...Taken together, this study revealed that miR-146a expression was decreased in small intestine ischemia and I/R injury. A …
Previous studies reported that miR-146a was involved in small intestine ischemia-reperfusion (I/R) injury, but the mechanism is large …
Effects of Zinc Source and Level on the Intestinal Immunity of Xueshan Chickens under Heat Stress.
Jin J, Xue M, Tang Y, Zhang L, Hu P, Hu Y, Cai D, Luo X, Sun MA. Jin J, et al. Animals (Basel). 2023 Sep 26;13(19):3025. doi: 10.3390/ani13193025. Animals (Basel). 2023. PMID: 37835631 Free PMC article.
Heat stress can cause intestinal inflammation, impaired barrier integrity, and decreased immunity in poultry. ...In conclusion, our study demonstrates that Zn-Prot M is superior to ZnS in improving intestinal immunity in Xueshan chickens, and 60 mg/kg is the optimal …
Heat stress can cause intestinal inflammation, impaired barrier integrity, and decreased immunity in poultry. ...In conclusion, our s …
Impact of Interleukin 10 Deficiency on Intestinal Epithelium Responses to Inflammatory Signals.
Papoutsopoulou S, Pollock L, Walker C, Tench W, Samad SS, Bergey F, Lenzi L, Sheibani-Tezerji R, Rosenstiel P, Alam MT, Martins Dos Santos VAP, Müller W, Campbell BJ. Papoutsopoulou S, et al. Front Immunol. 2021 Jun 16;12:690817. doi: 10.3389/fimmu.2021.690817. eCollection 2021. Front Immunol. 2021. PMID: 34220850 Free PMC article.
Interleukin 10 (IL-10) is a pleiotropic, anti-inflammatory cytokine that has a major protective role in the intestine. Although its production by cells of the innate and adaptive immune system has been extensively studied, its intrinsic role in intestinal epithelial …
Interleukin 10 (IL-10) is a pleiotropic, anti-inflammatory cytokine that has a major protective role in the intestine. Although its p …
Transcriptome Analysis Reveals Effect of Dietary Probiotics on Immune Response Mechanism in Southern Catfish (Silurus meridionalis) in Response to Plesiomonas shigelloides.
Wang R, Qian J, Ji D, Liu X, Dong R. Wang R, et al. Animals (Basel). 2023 Jan 28;13(3):449. doi: 10.3390/ani13030449. Animals (Basel). 2023. PMID: 36766339 Free PMC article.
The results also showed that inflammation-related genes, such as mmp9, cxcr4, nfkbia, socs3, il-8, pigr, tlr5, and tnfr1, were significantly upregulated in the PS group compared with those in the L-PS groups. In addition, we verified six DEGs (mmp9, cxcr4, nfkbia, s …
The results also showed that inflammation-related genes, such as mmp9, cxcr4, nfkbia, socs3, il-8, pigr, tlr5, and tnfr1, were signif …
Peanut allergen induces more serious allergic reactions than other allergens involving MAPK signaling pathways.
Wang J, Song R, Lan R, Hao M, Liu G, Liu M, Sun S, Chen C, Che H. Wang J, et al. Food Funct. 2022 Aug 30;13(17):8818-8828. doi: 10.1039/d2fo00777k. Food Funct. 2022. PMID: 35920097
Increased specific IgE, specific IgG1, allergic symptom scores, histamine, murine mast cell proteases-1, vascular leakage, Th2 cytokines, and mast cell infiltration in the lungs and intestine were found in the allergic groups via enzyme-linked immunosorbent assay, hematoxy …
Increased specific IgE, specific IgG1, allergic symptom scores, histamine, murine mast cell proteases-1, vascular leakage, Th2 cytokines, an …
Increased Intestinal Inflammation and Digestive Dysfunction in Preterm Pigs with Severe Necrotizing Enterocolitis.
Støy ACF, Heegaard PMH, Skovgaard K, Bering SB, Bjerre M, Sangild PT. Støy ACF, et al. Neonatology. 2017;111(4):289-296. doi: 10.1159/000452614. Epub 2016 Dec 24. Neonatology. 2017. PMID: 28013313
OBJECTIVES: We hypothesized that digestive dysfunction and intestinal inflammation are mainly affected by severe NEC lesions. METHODS: In 48 preterm pigs, the association between the macroscopic NEC score (range 1-6) and the expression of 48 genes related to inflammation, …
OBJECTIVES: We hypothesized that digestive dysfunction and intestinal inflammation are mainly affected by severe NEC lesions. METHODS …
The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection.
Jobin C, Sartor RB. Jobin C, et al. Am J Physiol Cell Physiol. 2000 Mar;278(3):C451-62. doi: 10.1152/ajpcell.2000.278.3.C451. Am J Physiol Cell Physiol. 2000. PMID: 10712233 Free article. Review.
The ubiquitous transcription factor NF-kappa B is a central regulator of the transcriptional activation of a number of genes involved in cell adhesion, immune and proinflammatory responses, apoptosis, differentiation, and growth. Induction of these genes in intestinal epit …
The ubiquitous transcription factor NF-kappa B is a central regulator of the transcriptional activation of a number of genes involved in cel …
Lactobacillus rhamnosus GG Promotes Recovery of the Colon Barrier in Septic Mice through Accelerating ISCs Regeneration.
Chen L, Li S, Peng C, Gui Q, Li J, Xu Z, Yang Y. Chen L, et al. Nutrients. 2023 Jan 28;15(3):672. doi: 10.3390/nu15030672. Nutrients. 2023. PMID: 36771378 Free PMC article.
Disruption of the intestinal barrier is both the cause and result of sepsis. The proliferation and differentiation of intestinal stem cells (ISCs) promote the regenerative nature of intestinal epithelial cells, repairing the injured intestinal mucosal …
Disruption of the intestinal barrier is both the cause and result of sepsis. The proliferation and differentiation of intestinal …
Piglet weight gain during the first two weeks of lactation influences the immune system development.
Lessard M, Blais M, Beaudoin F, Deschene K, Verso LL, Bissonnette N, Lauzon K, Guay F. Lessard M, et al. Vet Immunol Immunopathol. 2018 Dec;206:25-34. doi: 10.1016/j.vetimm.2018.11.005. Epub 2018 Nov 5. Vet Immunol Immunopathol. 2018. PMID: 30502909

Gene analysis by Q-PCR confirmed microarray results and revealed that IL-10, SOD1, NOS2, NOD2, TLR4, TLR9, CD40 and CD74 expressions were significantly decreased (P < 0.05) in LWG in comparison to HWG piglets, while MYD88 and NFkBiA showed a tendency to decrease (0.05 P

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Gene analysis by Q-PCR confirmed microarray results and revealed that IL-10, SOD1, NOS2, NOD2, TLR4, TLR9, CD40 and CD74 expressions were si …
187 results